Anti-DDR2 Polyclonal Antibody

商品货号：	商品品牌：	规格	基本售价：	选择规格
K001828P-50ul	solarbio	50ul	960.00元
K001828P-100ul	solarbio	100ul	1600.00元

英文名称	Anti-DDR2 Polyclonal Antibody
别名	MIG20a;NTRKR3;TKT;TYRO10
应用	WB IHC
稀释比例	WB 1:500-2000. IHC 1:50-200.
交叉反应	Human Mouse Rat
蛋白分子量	97kDa
Gene ID	4921
保存	Store at -20°C. Avoid freeze / thaw cycles.
储存液	Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法	Affinity purification
亚型	IgG
免疫原	Recombinant protein of human DDR2
性状	液体
Public Immunogen Range	Recombinant protein of human DDR2
Subcellular Locations	Cell membrane Single-pass type I membrane protein
Swiss Prot	Q16832
克隆类型	Polyclonal Antibody
背景资料	Receptor tyrosine kinases (RTKs) play a key role in the communication of cells with their microenvironment. These molecules are involved in the regulation of cell growth, differentiation, and metabolism. In several cases the biochemical mechanism by which RTKs transduce signals across the membrane has been shown to be ligand induced receptor oligomerization and subsequent intracellular phosphorylation. This autophosphorylation leads to phosphorylation of cytosolic targets as well as association with other molecules, which are involved in pleiotropic effects of signal transduction. RTKs have a tripartite structure with extracellular, transmembrane, and cytoplasmic regions. This gene encodes a member of a novel subclass of RTKs and contains a distinct extracellular region encompassing a factor VIII-like domain. Alternative splicing in the 5' UTR results in multiple transcript variants encoding the same protein.