Anti-VSV-M [23H12] Antibody-自主发布-资讯-生物在线

Anti-VSV-M [23H12] Antibody

作者:北京百奥创新科技有限公司 2023-03-10T17:06 (访问量:3032)

产品简介:This monoclonal antibody reacts with VSV-M protein.

产品优势:Reacts with VSV-M protein.Suitable for Western Blot applications.Vesicular stomatitis virus (VSV) is a well studied, enveloped, negative-strand RNA virus. The VSV genome encodes for 5 proteins: N, P, M, G, and L. The G protein (glycoprotein) is located at the virion surface and is responsible for virus attachment and penetration. Additionally, many lentivrial vectors are pseudotyped with VSV-G from the Indiana serotype.Vesicular stomatitis virus (VSV) is a well studied, enveloped, negative-strand RNA virus. The VSV genome encodes for 5 proteins: N, P, M, G, and L. The M protein (or matrix protein) is responsible for binding the nucleocapsid and condenses it into a tightly coiled helix and binds the nucleocapsid to the envelope. This activity of the M protein is what gives the virus its bullet like shape. In addition to M protein's role in virus assembly, it is also responsible for mediating molecular mechanisms of VSV pathogenesis. Wild-type M protein surpresses host gene expression in infected cells and inhibits antiviral responses.

抗原:VSV-M

宿主Mouse.

亚型:IgG2a kappa

克隆名称:23H12.

适应物种:Human.

免疫原:VSV infection.

应用范围:Western blot (1:1000).

储存:-20℃ (avoid repeated freeze / thaw cycles).

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